Hem-2 |
hemangiogenesis |
Insulin-receptor substrate-1 |
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[hemangioblast, hemangioblastic]
The term hemangioblast was introduced by Murray (1932) for bipotential precursor cells of blood cells and endothelial cells the existence of which had been postulated earlier in studies of blood development within the yolk sac in chicken embryos.
These cells are primitive precursor cells of mesodermal origin that have the capacity of differentiating into either hematopoietic cells (see: hemocytoblasts) or vascular endothelial cells (Sabin, 1920; Wagner, 1980; Schatteman, 2004) (see also: hematopoiesis, angiogenesis). They have been found in the aorta-gonad-mesonephros region
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