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dendritic epidermal T-cells

abbr. DETCs. These cells constitute a resident population of T-cells found in murine skin in symbiosis with keratinocytes. These cells are being referred to also as Skin Gamma-Delta T-cells.

Dendritic epidermal T-cells are derived from fetal thymic precursor cells and are significantly different from lymphoid Gamma-Delta T-cells and Alpha-Beta T-cells. They express an invariant form of the T-cell receptor found only in the skin, which recognizes antigens expressed on damaged, stressed, or transformed keratinocytes. Ye et al (2001) have shown that different cytokine receptors such as those for ... ... ... ... ... Subscribe to continue reading! ... ...

 

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