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delta-1

The murine delta-1 gene encodes a protein of 359 amino acids (Fujio et al, 2000). It is a member of the Type 1 cytokine receptor family. The extracellular domain of the protein shares homology with common gamma, a receptor subunit found in the receptors for various interleukins.

The human counterpart has been identified as CRLM-2. The protein has been identified independently as one receptor component for murine thymic stromal lymphopoietin (TSLP) (Park et al, 2000).

The human homolog is dll1.

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