Death Defying Domain |
death domain 1 |
Colony-forming unit granulocyte inhibitory factor |
||
[death domains]
(abbr. DD) This domain of approximately 80 amino acids was identified by deletion analysis in the C-terminal intracellular region of the 55 kDa receptor for TNF (TNFR1) (Tartaglia et al, 1993; Boldin et al, 1995; Baker and Reddy, 1996). A similar region with many of the amino acids conserved has been identified in the FAS antigen (see: APO-1). The death domain derives its name from the fact that it is involved in signaling processes ultimately leading to programmed cell death by apoptosis (Feinstein et al, 1995; Hofmann and Tschopp, 1995).
The death domain is a protein-protein interaction motif
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |
| SUPPORT COPE | Intro | Subdictionaries | New Entries | Contribute data | COPE Credentials |
| # | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z |
|
Created, developed, and maintained by Dr H Ibelgaufts
|
U L T R A P O S S E N E M O O B L I G A T U R