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cell death caspases

The term cell death caspase (also: apoptotic caspases or pro-apoptotic caspases) refers to some members of a group of evolutionarily conserved cysteine proteases the cleavage substrate of which contains an aspartate residue (a cysteine aspartase; see: caspases) (for overview see: Wallach et al, 2010). Cell death caspases are involved directly or indirectly in processes leading to cell death by apoptosis but also other forms of cell death and are classified usually as initiator caspases (caspase-2, caspase-8, caspase-9, and caspase-10) and executioner caspases (caspase-3, ... ... ... ...
 
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Entry last modified: November 2010



 
 
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