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Xenopus laevis antibacterial peptide-P1

abbr. XLAsp-P1. This small peptide, DEDDD, has been isolated from the skin of Xenopus laevis. The peptide shows strong in vitro potency against a variety of Gram-positive bacteria and Gram-negative bacteria. It is also an anticancer peptide with potent inhibitory activity against breast cancer cell at tested concentrations from 5 to 50 μg/mL. Only 6.2 % of red blood cells show hemolysis at 64 μg/mL Li et al, 2016).

For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also: Innate immunity and defense peptides Dictionary.

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