COPE Media Kit


Cope Home
Previous entry:
Vaccinia virus B8R protein
Next entry:
Vaccinia virus B14R protein
Random entry:
MuSCs
Search COPE:

Vaccinia virus B14 protein

[Vaccinia virus B14R protein] This protein is encoded in the genome of Vaccinia virus. The protein has the same three-dimensional fold as BCL2 family proteins despite lacking identifiable sequence similarity but does not modulate cell death by apoptosis (Graham et al, 2008).

The protein promotes immune evasion and virulence. It is non-essential for virus replication in cell culture but contributes to virus virulence in vivo and affects the host response to infection (Chen and Smith, 2006).

Protein B14 binds to an endogenous inhibitor of the pro-inflammatory tanscription factor NF-kappa-B, IKK-beta and thereby reduces phosphorylation of I-kappa-B-alpha (Benfield et al, 2011).

... ... ... ...
 
... CONTINUE READING at cells-talk.com, COPE's new home with 61 100+ entries, 141 552 cited references and >2,5 million internal hyperlinks. This most comprehensive knowledge base provides extensive in-context information covering nomenclature, terminology, and highlighting concepts, strategies & complexities of cellular communication processes. COPE's fully integrated subdictionaries include Dictionary of Angiogenesis Dictionary of Antimicrobial & host defense peptides Dictionary of Apoptosis and cell death Dictionary of CD antigens Dictionary of Chemokines Dictionary of Cryptides Dictionary of Cytokines & Growth factors Dictionary of Eukaryotic cell types & expression profiles Dictionary of Hematopoiesis Dictionary of Hormones Dictionary of Inflamation & inflammatory mediators Dictionary of Innate Immunity Dictionary of Metalloproteinases Dictionary of Moonlighting proteins & cryptides Dictionary of Neuropeptides Dictionary of Pathogenicity & Virulence Factors Dictionary of Pattern recognition receptors Dictionary of Protein domains Dictionary of Regulatory peptide factors Dictionary of Viroceptors Dictionary of Virokines Dictionary of Stem cells and more.
 
An important note about your privacy: A search engine may have brought you here. If the provided URL differs in any way from "www.copewithcytokines.org/cope.cgi?key=search term", 3rd parties may record your activities on COPE. Bypass snoopers by doing this: Go directly to cells-talk.com or go to copewithcytokines.org in a new browser tab and from there explore whether COPE contains the terms that interest you. The private bioinformatics initiative COPE at cells-talk.com never shares your search histories or user databank entry with 3rd parties.

Copyright © 1997-2025. All rights reserved by Dr H Ibelgaufts, the sole author/owner/maintainer of the COPE Knowledge Base. EXPLICITLY: COPE's contents are strictly for the personal use of subscribers. They aren't in the public-domain and may not be reproduced elsewhere or transmitted in any form!

Entry last modified: July 2015



 
 
SUPPORT COPE | Intro | Subdictionaries | New Entries | Contribute data | COPE Credentials
# A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

              Created, developed, and maintained by Dr H Ibelgaufts              
About the author of COPE
  |    Contact COPE   |    Terms & Conditions


U L T R A   P O S S E    N E M O   O B L I G A T U R



cope.cgi Version 1.41 [08.12.2020]. (c) JI. Powered by Perl 5.032001. key=58447