VKVGINGFGRIGRLVTRAAFHGKKVEVVAIND |
VLA-2 |
Mothers against DPP homolog 9a |
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[VLA-1(+), VLA-1(-), VLA-1(low), VLA-1(high), VLA-1(int)]
[very late activation antigen 1] Very late activation antigens are a family of heterodimeric transmembrane proteins that belong to the integrin family of cell adhesion molecules (Hynes, 1987; Ruoslahti, 1991). These antigens consist of a distinct alpha subunit non-covalently linked to a common beta subunit. Their name refers to the observation that beta-chains increase in amount and additional alpha-subunits appear after long-term T-cell activation (Hemler et al, 1987).
Based on its identity with ITGA1 [integrin-alpha-1], VLA-1 is being referred to also as VLA-alpha 1 [very late activation antigen alpha-1].
In the
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