Thrombospondin-2
abbr. TSP2; gene symbol THBS2. This protein has been identified by LaBell et al (1992) by sequence homology of its cDNA towards human thrombospondin-1. Thrombospondin-2 and related proteins are characterized by a number of protein domains known as thrombospondin type 1 repeats, thrombospondin type 2 repeats, thrombospondin type 2 repeats.
The TSP2 gene is expressed in fibroblasts, smooth muscle cells, an osteosarcoma cell line, and Swiss 3T3 cells, but not in umbilical vein endothelial cells. The protein can form heterotrimeric complexes with thrombospondin
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