TREML1

approved gene symbol. [triggering receptor expressed on myeloid cells-like 1; TREM-like protein 1] abbr. also TLT-1 [Trem-like transcript 1 protein] (Washington et al, 2002).

Washington et al (2002) have identified human and mouse TREML1. The receptor contains an inhibitory ITIM motif and a sequence that can interact with SH3 domains. TREML1 is expressed abundantly in bone marrow, but not in lymphocytes. The protein is expressed exclusively in platelet alpha granules and megakaryocytes. Its expression is up-regulated dramatically upon platelet ... ... ... ...
 
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Entry last modified: November 2011