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TRAMP

[TNF receptor apoptosis-mediating protein] Human TRAMP (363 amino acids) is most homologous to the type 1 TNF receptor. TRAMP is identical with APO-3, DR3, wsl-1, or LARD. It has been described as TR3 (TNF receptor-like-3). Owing to its homology to other members of the TNF receptor superfamily the receptor is being referred to also as TNFRSF12 [TNF receptor superfamily member 12].

TRAMP is expressed abundantly on thymocytes and lymphocytes. Its cytoplasmic region contains a death domain known to be involved in signaling cell death ... ... ... ... ... Subscribe to continue reading! ... ...

 

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