TIA-like-1 |
TIAR |
macrocytes |
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[Thiol inhibitor of apoptosis] This murine protein belongs to the inhibitor of apoptosis (IAP) family of proteins, which form a highly conserved gene family that prevents cell death by apoptosis in response to a variety of stimuli (Kobayashi et al, 1999). TIAP appears to be a murine homolog of human survivin and thus is murine BIRC5 [baculoviral IAP repeat-containing protein-5] (Survivin).
TIAP interacts with the processed form of caspase-3 and inhibits cell death induced by activation of caspases
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