TAPA-1
[target of antiproliferative antibody 1] Oren et al (1990) have isolated the cDNA coding for human TAPA-1. The human and murine gene show a high level of homology (Andria et al, 1991).
TAPA-1 is an integral membrane protein of 26 kDa expressed on many human cell types. Antibodies against TAPA-1 induce homotypic aggregation of cells and inhibits their growth. In the nomenclature of CD antigens this protein has been given the designation CD81 (Engel and Tedder, 1994).
For additional information on CD antigens see also: CD antigens Dictionary.
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