SARAH domain |
Sarcolectin binding protein |
neural epidermal growth factor-like 2 |
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abbr. SCL. The approved gene symbol is KRT7 [keratin-7] (designated K7 by Glass and Fuchs, 1988); termed also Cytokeratin-7. Sarcolectin is a secreted endolectin of 55 kDa (Jiang et al, 1999) that has been identified in sarcoma and normal hamster tissues as a protein that agglutinates normal and transformed cells and that reduces the antiviral state pre-established by IFN-alpha and IFN-beta (Jiang et al, 1983, 1984). The protein has been found also in human sarcomas, placenta tissue, and muscles. It is secreted from cultures of human embryonic fibroblasts, human osteosarcoma and
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