SOCS5 |
SOCS7 |
VDPP |
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[Suppressor of cytokine signaling-6] This protein (Starr et al, 1997) is a member of the SOCS protein family. It functions as a regulator of cytokine signaling by interfering with signal transduction pathways involving mediators such as Janus kinases and STAT proteins and has been described independently as CIS4 [Cytokine inducible SH2-containing protein-4]. Another designation is CISH4 [Cytokine inducible SH2-containing protein-4]
Mooney et al (2001) have reported that SOCS6 associates with and inhibits the insulin receptor. SOCS6 binds to insulin receptor
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