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SIGLEC-12

[sialic acid binding immunoglobulin-like lectin 12] This protein is a member of a family of type 1 transmembrane proteins known as SIGLECs. They are cell surface lectins that have the ability to bind to sialic acids and mediate interactions between proteins and carbohydrates. Several studies describing the sialoside specificities of individual SIGLECs have been reported (Blixt et al, 2003; Rapoport et al, 2006).

SIGLEC-12 is the new designation for a protein described originally as SLG [SIGLEC-like gene] and S2V. The protein is known also as SIGLECL1 [SIGLEC-like 1]

SLG [SIGLEC-like gene] has been identified by Foussias et al (2001). A short isoform ( ... ... ... ... ... Subscribe to continue reading! ... ...

 

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