S100A7L2 |
S100A8/A9 |
Macrophage inflammatory protein-related protein-1 |
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[S100 calcium binding protein A8] This protein is related to S100. It is identical with MRP-8 [migration inhibition factor-related protein-8 or myeloid-related protein-8] (see: Calgranulins). Together with S100A9 it constitutes the cystic fibrosis antigen. The complex of S100A8 and S100A9 is frequently being referred to as S100A8/A9 [S100 calcium-binding proteins A8/A9].
Cross et al (2005) have reported overexpression of the protein together with other members of the S100 family in common cancers. Lee et al (2008) have reported that S100A8 plays an anti-apoptotic role in X-ray irradiated keratinocytes
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