Renin
approved gene symbol: REN. This enzyme is sometimes being referred to also as Angiotensin-forming enzyme or Angiotensinogenase. In the enzyme nomenclature it has received the designation EC3.4.23.15 (formerly EC3.4.4.15 and EC3.4.99.19).
The human cDNA has been cloned by Imai et al (1983), and the gene structure has been reported by Hobart et al (1984) and Hardman et al (1984).
The terms Ren1 (Renin 1) refers to the mouse and rat gene (Kim et al, 1989). Some mouse strains, for example the widely used 129 strain or
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