ROSA

This mast cell cell line has been generated by Saleh et al (2014) from the CD34(+) fraction of normal umbilical cord blood cells. ROSA cells constitute a factor-dependent cell line as the cells, termed also ROSA(KIT WT) (for wild-type), require stem cell factor for growth. ROSA(KIT WT) cells stain strongly positive for tryptase and kit, but express only little if any chymase. The cells do not express CD2 or CD25 but express Fc-epsilon-RI, kit (CD117), ... ... ... ...
 
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Entry last modified: March 2017