PYP |
PYPAF2 |
AvBD4 |
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[Pyrin-containing APAF-1-like protein 1] The approved gene symbol is NLRP3 [NLR family, pyrin-domain containing 3; NACHT domain Leucine-rich repeat and PYD-containing protein 3]. For a viral counterpart see also: vPOP [viral PYD-only protein; viral pyrin-only protein 1]. The gene has been identified independently as AGTAVPRL [Angiotensin/vasopressin receptor AII/AVP-like, AII/AVP-like].
This protein is a member of a protein family characterised by the presence of a Pyrin domain, a nucleotide binding site, and a leucine-rich repeat motif (LRR
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