NLRP2 |
NLRP3 inflammasome |
B7-1 |
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[NLR family, pyrin-domain containing 3; NACHT domain Leucine-rich repeat and PYD-containing protein 3] This is the approved gene symbol for PYPAF1 [Pyrin-containing APAF-1-like protein 1]. The terms NLRP3P [NLR family, pyrin-domain containing 3 pseudogene] or NLRP3P1 [NLR family, pyrin-domain containing 3 pseudogene 1] refer to a pseudogene (Inohara and Nuñez, 2003).
The protein is a member of the CLR family (NLR family) and is known also as CLR1.1. For nomenclature see also: Ting et al (2008). NLRP3 is a component of a structure involved in inflammatory cell death,
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