paravascular cells |
PARCS |
3T3-L1 adipocytes |
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[pulmonary and activation-regulated chemokine] This factor belongs to the CC-Chemokines. It was identified initially by searching the expressed sequence tag (EST) database for sequences related to MIP-1-alpha (Hieshima et al, 1997). The complete cDNA sequence contains an open reading frame of 89 amino acids (including a signal sequence of 20 amino acids) with 61 % identity to human MIP-1-alpha or LD78-alpha. PARC is referred to also as AMAC-1 (alternative activated macrophage associated CC-Chemokine), MIP-4 (macrophage inflammatory protein-4), or DC-CK1. The factor has been
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