PANO1 |
PANoptosomes |
Corticotropin releasing factor-binding protein |
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this term has been coined to describe a mechanism of inflammatory cell death that combines features of several cell death modes (pyroptosis, apoptosis, and necroptosis) and the various multi-component assemblies (inflammasomes) involved in their execution (Malireddi et al, 2019). Multi-complexes, termed PANoptosomes, connect components of pyroptosis (inflammasome sensors, caspase-1 and caspase-11) with components of apoptosis (caspase-8 caspase-7, and PARP), and components of necroptosis (RIPK1 and RIPK3
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