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OX19

The mouse monoclonal antibody of this name recognizes a cell surface glycoprotein of 69 kDa on virtually all rat thymocytes, T-lymphocytes and a maximum of 2 % B-lymphocytes (Dallman et al, 1984). No reactivity is observed with nonlymphoid cells in intestine, thymus, spleen, and lymph node. The OX19 antibody itself is not mitogenic but it increases the proliferation of T-cells stimulated by allogeneic spleen cells or the lectins phytohemagglutinin and concanavalin A. This is accompanied by the production of IL2. The OX19 antigen is considered to be the equivalent of mouse Ly1 antigen and ... ... ... ... ... Subscribe to continue reading! ... ...

 

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