OSAD |
OSCAR-like transcript-1 |
NPH4 |
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approved gene symbol; [osteoclast-associated receptor] also: osteoclast-associated immunoglobulin-like receptor. A databank synonym is PIgR3 [Polymeric immunoglobulin receptor 3; Poly-Ig receptor 3].
The cDNA for the murine and human receptor (263 amino acids, 73 % identity) has been cloned by Kim et al (2002). The receptor contains 2 extracellular immunoglobulin-like domains. This receptor is expressed specifically on osteoclast lineage cells and regulates osteoclastogenesis (Kim et al, 2002). Murine macrophages
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