Neuroblastoma-derived sulfhydryl oxidase |
Neuroblastoma growth inhibitory factor |
LH-alpha |
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This biochemically uncharacterized factor of less than 5 kDa is detected in von Recklinghausen neurofibroma extracts. It promotes the proliferation of human neuroblastoma cells and the survival and neurite-extension of rat cortical neurons.
Distinct growth factors for human neuroblastoma cells are also VIP (vasoactive intestinal peptide), IGF-2, and TNF-alpha.
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