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[nonspecific cytotoxic cell antimicrobial protein-1; NCC antimicrobial protein-1] NCAMP-1 has been identified originally in channel catfish (Ictalurus punctatus) nonspecific cytotoxic cells (Evans et al, 2005). Sequence comparisons of this protein indicate similarity to zebrafish (51.2%) histone family member 1-X and (to a lesser extent) to trout histone H1.

NCAMP-1 has been shown to bind GpC and CpG oligodeoxynucleotides and may function as a pattern recognition protein (Kaur et al, 2005; Evans et al, 2005).

Connor et al (2009) have reported that the protein is expressed on nonspecific cytotoxic cell membranes and is found also in granule extracts from these cells ... ... ... ... ... Subscribe to continue reading! ... ...


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