MDC

This term has multiple meanings:

(-1-) Human macrophage-derived chemokine

This factor appears to be synthesized specifically by cells of the macrophage lineage. MDC is expressed highly in macrophages and in monocyte-derived dendritic cells, but not in monocytes, natural killer cells, or several cell lines derived from epithelial cells, endothelial cells, or fibroblasts. High expression is detected in normal thymus and less expression in lung and spleen. MDC is expressed together with two other chemokines, Fractalkine and TARC, by a subset of ... ... ... ...
 
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Entry last modified: January 2002