MAQDIISTIGDLVKWIIDTVNKFTKK |
MARC |
cytotoxic T-lymphocyte-associated serine esterase-1 |
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[Mouse-activating receptor 1] This murine protein is the murine homolog of the human NK-cell receptor NKp46. Similar to human NKp46, MAR-1 is expressed selectively by NK-cells and acts as a triggering receptor involved in the induction of natural cytotoxicity.
The MAR-1 protein displays 58 % identity with human NKp46 receptor. In the nomenclature of CD antigens this protein has been given the designation CD335.
For additional information on CD antigens see also: CD antigens Dictionary.
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