LFA-1
[LFA-1(+), LFA-1(-), LFA-1(+/-), LFA-1(high), LFA-1(low)]
[lymphocyte function-associated antigen-1] This is the same as LFA-1-alpha [lymphocyte function-associated antigen-1-alpha]. LFA-1 has been identified originally as an antigen associated with human T-lymphocyte mediated cytolysis (Sanchez-Madrid et al, 1982; Krensky et al, 1983).
LFA-1 has been identified as a receptor for extracellular secreted ISG15 [interferon-stimulated gene-15] (see).
In the nomenclature of CD antigens this protein has been given the designation CD11a.
For additional information on CD antigens see also: CD antigens Dictionary
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