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KU-19-19

a human carcinoma cell line established from an invasive transitional cell carcinoma of the bladder. The cells form tumors in nude mice and this is associated with the presence of severe neutrophilia in the peripheral blood.

The conditioned medium of this cell lines stimulates the incorporation of tritiated thymidine of growth factor-dependent hematopoietic cell lines and has been shown to contain high amounts of G-CSF (> 5 ng/mL) and also GM-CSF, M-CSF, SCF, IL1-alpha, IL6, and IL8. Pretreatment with phorbol esters, ... ... ... ... ... Subscribe to continue reading! ... ...

 

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