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KIF7

[kinesin family member 7] KIF7 is considered an ortholog of Drosophila melanogaster costal-2 (Katoh and Katoh, 2004), a protein regulating signalling of the morphogen Hedgehog at various levels. Costal-2 can substitute for KIF7 functions (Maurya et al, 2013), which demonstrates that the functions of the vertebrate and invertebrate proteins have been conserved. Unlike Costal-2, KIF7 is associated with the primary cilium (Liem et al, 2009), a non-motile organelle that emanates from the surface of multiple cell types and responds to mechanical stimuli and also acts as a chemosensor.

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