Morphogenetic Neuropeptide |
morpholinos |
Rotamase A(63-92) |
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[morphogen]
This general term refers to any kind of locally produced, secreted protein that forms spatial and/or temporal gradients in developing tissues. Morphogens provide inductive signals that act over long distances, provide cells with positional information, and control growth and patterning during embryonic/tissue development (for overview see: Briscoe and Small, 2015; Rogers and Schier, 2011; Sagner and Briscoe, 2017).
Important morphogens include members of the Wnt family, various Hedgehog proteins (Desert hedgehog homolog, Indian hedgehog homolog, Sonic hedgehog homolog), members of the TGF-beta superfamily (which includes TGF-beta, Activins, Inhibins,
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