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KHF

[killer cell helper factor] KHF activities of 15-20 kDa and 45-50 kDa were initially isolated as proteins that promote the development of thymocytes after cell activation into cytotoxic T-cells. The 15-20 kDa factor has been shown to be identical with IL2 (Kaieda et al, 1982).

The other KHF activity may be due to IL5 and IFN-gamma (see also: Th1 cytokines, Th1 cytokines) (Takatsu et al, 1987). For nomenclature see also: Mizel and Farrar (1979).

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