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JFCCL3

JFCCL3 is a CC-Chemokine gene cloned from Japanese flounder, Paralichthys olivaceus. The JFCCL3 cDNA encodes a protein of 95 amino acid residues. The genomic sequence consists of two isoforms: JFCCL3.1 and JFCCL3.2. JFCCL3 is expressed constitutively in most tissues including lymphoid organs. JFCCL3 is more closely related to fractalkine than to other mammalian beta-Chemokines. JFCCL3 is chemotactic for Japanese flounder leukocytes.

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