IgE-HRF

[IgE-dependent histamine releasing factor] IgE-HRF produced by lymphocytes of atopic children and present in biological fluids of allergic patients has been purified by MacDonald et al (1995). The protein is identical with the human growth-related tumor protein p23, a protein of Ehrlich ascites tumor cells synthesized preferentially in the exponentially growing tumor (Böhm et al, 1989). p23 is identical with TCTP (translationally controlled tumor protein). The human gene (TPT1) maps to chromosome 13q12-q14 (McDonald et al, 1999). For comparison see also: Histamine releasing factors.

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Entry last modified: January 2020