IL17E

[interleukin-17E] IL17E is a member of the IL17 family of cytokines, showing approximately 20 % homology with IL17, IL17B, and IL17C (Lee et al, 2001). IL17E does not bind to the IL17 receptor. It is a ligand for the receptor protein termed Evi27 (IL17 receptor homolog-1) (Lee et al, 2001). IL17E stimulates production of the pro-inflammatory chemokine IL8. It has been shown to induce activation of NF-kappa-B (Lee et al, 2001). Hurst et al (2002) have identified the murine IL17E homolog, which they termed IL25 [ ... ... ... ...
 
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Entry last modified: November 2011