IL1-beta-1 |
IL1-beta(163-171) |
Matrigel plug assay |
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[interleukin-1-beta-2] This term refers to a second IL1-beta gene in rainbow trout (Oncorhynchus mykiss) (Pleguezuelos O et al, 2000). The amino acid sequence has 82 % similarity to the first gene, termed also IL1-beta-1, 45 % similarity to carp IL1-beta, and 40 % similarity to human IL1-beta. Comparison of the two trout genes reveals that the IL1-beta-2 gene has a deletion of 9 bases in exon 3 and an altered splicing site at the 5' end of exon 4 giving rise to a further 9-bp deletion in the resulting cDNA. IL1-beta-2 expression is induced in cultured trout leukocytes by stimulation with
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