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IGSF8

[immunoglobulin superfamily member 8] This is the approved gene symbol for a protein identified independently as PGRL [prostaglandin regulatory like], KASP [KAI1/CD82-associated surface protein], EWI-2 [EWI motif-containing protein 2; glutamine-tryptophan-isoleucine-2].

The genomic organization of mouse and human IGSF8 has been described by Murdoch et al (2003). The protein shows a dynamic expression pattern during embryonic and fetal development. Ventral, but not the dorsal, domain of neural tube expression is dependent on SHH signaling. From E11.5, IGSF8 is expressed at the lateral edge of the ventricular zone, in early ... ... ... ... ... Subscribe to continue reading! ... ...

 

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