SHF cells |
SH-HSCs |
AADISQWAGPL |
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[Sonic hedgehog; Sonic hedgehog homolog] SHH is a member of the hedgehog gene family comprising Sonic hegehog, Indian hedgehog, and Desert hedgehog (Marigo et al, 1995). SHH has been identified independently as vhh-1 [vertebrate hedgehog homolog 1] in the rat and Hhg-1 in the mouse.
The mammalian factors encoded by these genes are homologs of a Drosophila melanogaster gene that regulates pattern formation. The mammalian gene products
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