dormancy-associated miRNAs |
Dorsal Gamma-Kenyon cells |
UNC5B |
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Dorsal, identified by Steward (1987), is encoded by the Drosophila melanogaster gene CG6667. It is one of three NF-kappa-B family members found in Drosophila (the others being Dif [Dorsal-related immunity factor] and Relish).
Dorsal, has been shown to play a central function in dorso-ventral axis formation in the embryo (Govind, 1999), but also regulates innate immune responses. Dorsal is dispensable in adults but can substitute for Dif [Dorsal-related immunity factor] in controlling the expression of the antimicrobial peptide Drosomycin in mutant larvae lacking expression of Dif. The gene encoding the antibacterial
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