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Dorsal

Dorsal, identified by Steward (1987), is encoded by the Drosophila melanogaster gene CG6667. It is one of three NF-kappa-B family members found in Drosophila (the others being Dif [Dorsal-related immunity factor] and Relish).

Dorsal, has been shown to play a central function in dorso-ventral axis formation in the embryo (Govind, 1999), but also regulates innate immune responses. Dorsal is dispensable in adults but can substitute for Dif [Dorsal-related immunity factor] in controlling the expression of the antimicrobial peptide Drosomycin in mutant larvae lacking expression of Dif. The gene encoding the antibacterial ... ... ... ... ... Subscribe to continue reading! ... ...

 

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