ICAM1(+) neutrophils |
ICAM3 |
endotoxins |
||
(approved gene symbol) [intercellular adhesion molecule 2] In the nomenclature of CD antigens this protein has been given the designation CD102.
ICAM2 has been identified and named by Staunton et al (1989) by a functional DNA cloning method in search of proteins that allow leukocyte adhesion in the presence of antibodies blocking the function of the adhesion molecule ICAM1, which is a ligand for the LFA-1 receptor. ICAM2 is an integral membrane protein with two immunoglobulin-like domains, which are homologous with the first two immunoglobulin domains in ICAM1
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