Hematopoietin receptor superfamily |
HEMbeta111-146 |
Beta-END |
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This is a generic name given to Hematopoietic growth factors (abbr. HGF) or Hematopoietic cytokines, which act on cells of the hematopoietic system (see: hematopoiesis, hematopoietic stem cells). These factors are active at all stages of development.
Hematopoietic growth factors are produced by many different cell types including those not belonging to the hematopoietic system. These factors are either secreted or they exist in membrane-bound or matrix-associated forms. They may have different modes of action also, such as autocrine, paracrine, or juxtacrine
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