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HMGN1

[high mobility group nucleosome binding domain 1; high mobility group nucleosomal binding protein 1]. This protein is known also as HMG14 [high mobility group protein 14].

HMGN1 is a non-histone nucleosome-binding protein in the nucleus that belongs to the HMG N family of proteins. It shows no homology to HMGB1. HMGN1 is a chromatin remodelling protein that reduces the compaction of the chromatin fiber and has been shown to enhance the stress-induced phosphorylation of histone H3 Lim JH et al, 2004) and histone H2A (Postnikov et al, 2006), and acetylation of histone H3 (Lim JH et al, 2005). Lane et al (2000) have reported that HMGN1 also influences the methylation of histone H3 ... ... ... ... ... Subscribe to continue reading! ... ...

 

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