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histone H3

Histone H3 is a core component of nucleosomes that compact DNA into chromatin (DeLange and Smith, 1971). Histone H3 constitutes a multigene family of replication-dependent histones that are expressed mainly during S phase and replication-independent histones, or replacement variant histones expressed throughout the cell cycle. There are only slight differences between the encoded proteins (see: Marzluff et al (2002) for overview). Apart from its role in chromatin, Histone H3 has other functions and thus can be regarded as a member of a growing group of proteins referred to as moonlighting proteins.



Role as moonlighting protein

Tagai et al (2011) have reported an antimicrobial activity of calf thymus histone H3 for Escherichia coli ... ... ... ... ... Subscribe to continue reading! ... ...

 

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