HLS5

[hemopoietic lineage switch 5] This gene has been described by Lalonde et al (2004). It has been described independently as MAIR [Macrophage-derived Apoptosis-Inducing RBCC protein]. The approved gene symbol is TRIM35 [tripartite motif-containing protein 35]. HLS5 is a gene expressed by the monocytoid variant cells obtained from the J2E erythroleukemic cell line, but not the parental J2E cells. HLS5 is expressed in a wide range of adult tissues; however, at different stages during embryogenesis, HLS5 is detected in the branchial arches, spinal cord, dorsal root ganglia, limb buds, and brain.

Endersby et al (2008) have shown that HLS5 impedes erythroid cell ... ... ... ...
 
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Entry last modified: March 2023