GLP-1 receptor |
GLP2R |
ANLERTFIAIKPDGV |
||
[glucagon-like peptide-2] GLP-2 (bioactive form designated also GLP-2(1-33)) is a peptide hormone of 33 amino acids (HADGSFSDEMNTILDNLAARDFINWLIQTKITD; His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp) encoded by the preproglucagon gene (see also: glucagon), which gives rise also to the related peptide hormones GLP-1 and Glucagon. GLP-2 corresponds to PG(126-158) [proglucagon(126-158)] (see: Holst, 1997).
The GLP-2 sequence is encoded carboxyterminal to the sequence of GLP-1 in the proglucagon
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