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FS-1

a human stromal cell line derived from the bone marrow of a patient with chronic myelogenous leukemia in blast crisis (Kato et al, 1996). The cells have not been immortalized by introduction of the SV40 T antigen (see also: Stromal cell line).

FS-1 cells have a fibroblastoid morphology. The cells do not express markers of hematopoietic cells and are negative for alpha-naphthyl acetate esterase, acetylated LDL, von Willebrand factor. The cells are not phagocytotic. The cells express acid phosphatase, alkaline phosphatase, collagen type 1, collagen type 3, collagen type 4, and fibronectin. The cells express ... ... ... ... ... Subscribe to continue reading! ... ...

 

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