EVA1A

[eva-1 homolog A] this protein, which is a homolog of the corresponding Caenorhabditis elegans gene, is known as FAM176A [family with sequence similarity 176 member A] and TMEM166 [transmembrane protein 166].

Role in autophagy and apoptosis

Wang L et al (2007) have identified the human EVA1A as a protein associated with lysosomes and the endoplasmic reticulum. It colocalizes with autophagosomes and promotes cell death by apoptosis and autophagy. Overexpression of EVA1A markedly inhibits colony formation in HeLa ... ... ... ...
 
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Entry last modified: September 2023