estromedins |
ET-1 |
Leu-Glu-Ala-Asp-aldehyde |
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ALTERNATIVE NAMES
EDCF [endothelium-derived contracting factor]. See also: individual entry for further information.
SOURCES
Endothelins are produced and secreted by endothelial cells and epithelial cells. ET-1(1-31) (CSCSSLMDKECVYFCHLDIIWVNTPEHVVPY), a peptide derived from the 38 amino acid big endothelin precursor, is a major endothelin derivative that is a potent chemotactic peptide for human neutrophils and monocytes (Cui et al, 2001).
The synthesis of
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